Bifunctional catalysis
نویسنده
چکیده
Bifunctional catalysis concerns the use of low molecular weight, structurally defined molecules possessing two distinct functional groups to bring about new reactivity and/or selectivity in a reaction of interest. The reactions are typically polar addition reactions of pronucleophiles and electrophiles where, ideally, simple low-cost starting materials are converted into high-value, stereochemically defined products through the action of the bifunctional catalyst system.
منابع مشابه
Catalytic phosphorylation using a bifunctional imidazole derived nucleophilic catalyst.
A bifunctional catalyst containing a polyether backbone and a nucleophilic imidazole moiety has been prepared that demonstrates cooperative catalysis in the presence of added group 1 and 2 salts for the phosphorylation of alcohols.
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Cinchona alkaloid derivatives modified to include a (thio)urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.
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